The development of PDE5-inhibitors is a clear example of how Western medicine approached the problem of ED differently from Eastern medicine. The erectogenic effect of sildenafil (Viagra®) was discovered by accident when patients undergoing heart clinical trials reported better erections as a side effect after taking sildenafil. This observation led to further elucidation of the NO/cGMP signalling pathway and development of PDE5-inhibitors as a first-line therapy in ED (5).

In addition, when research has shown a nutrient such as zinc or niacin to improve sexual function, it's usually in people who are deficient in it. So, before you stock up on over-the-counter nutritional supplements for ED, speak with your doctor. He can test you for deficiencies and steer you toward the most effective and safest way to treat your erectile dysfunction. 

Peanuts contain a trove the amino acid L-arginine, which is one of the building blocks of nitric oxide, which aids your efforts under the covers. They also help reduce cholesterol levels. The less cholesterol you have in your system, the easier it is for blood to circulate throughout your body and down, which can help you maintain a firmer erection longer.
In addition to being leaner and lower in calories than conventional cuts, grass-fed beef offers a host of benefits, from muscle-building to fat-burning to heart protection. You can add assistance in the bedroom to its list of good qualities; it’s an excellent source of Vitamin B12. A recent report from Harvard University highlighted a study that has linked low levels of B12 to erectile dysfunction. So, eat up! Bonus: It’s one of the healthy fats that actually makes you skinny.
Eastern medicine should be fully exploited, and integrated with modern medicine to combine the advantages of both TCM and Western medicine. More research should be conducted into the efficacy and safety of TCM, and integration of TCM and Western medicine may provide promising breakthroughs in future clinical treatment. This strategy may allow for the development of new therapeutic strategies based on concepts of TCM and integrated medicine. There is a need for multimodal therapy and holistic approach to treat men (and their partners) with ED through complementary use of herbal supplements and modern drug to optimize underlying medical comorbidities; acupuncture, exercise or massage to reduce stress and strengthen the body; introduction and escalation of various medical therapy with use of mechanical therapy to further enhance penile erection; and lastly surgical intervention in suboptimal or refractory ED cases.
"The problem with alternative treatments for any medical problem, including erectile dysfunction, is that until you have about 20 well-controlled studies over several years, you really don't know what you are working with," cautions Richard Harris, MD, a urologist at Gottlieb Memorial Hospital, part of the Loyola University Health System in Chicago.

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 9 Jan 2019), Cerner Multum™ (updated 14 Jan 2019), Wolters Kluwer™ (updated 7 Jan 2019) and others. Refer to our editorial policy for content sources and attributions.


The penile roots are enveloped by two pelvic floor muscles, the bulbocavernosus (BC) and the ischiocavernosus (IC). The IC muscle is the “erector muscle” and the BC muscle the “ejaculator muscle.” The BC and IC muscles are responsible for the ability to lift one’s erect penis up and down (wag the penis) as they are contracted and relaxed. Although not muscles of glamour, they are certainly muscles of “amour.” Although unseen and behind-the-scenes, hidden from view, these often unrecognized and misunderstood muscles have vital functions in addition to erection and ejaculation. When the pelvic floor muscles are not functioning optimally, one loses the potential for full erectile rigidity. Like other skeletal muscles, they can undergo “disuse atrophy,” becoming thinner, flabbier and less functional with aging, weight gain, sedentary lifestyles, poor posture, chronic straining and other forms of trauma, including pelvic surgery (e.g., prostatectomy). Exercising them can enhance sexual health; maintain sexual health; help prevent the occurrence of ED in the future; and help manage ED. Specifically, pelvic floor exercises can be beneficial with respect to the following spectrum of issues: ED; ejaculation issues including premature ejaculation; urinary incontinence; overactive bladder; post-void dribbling; and bowel urgency and incontinence. One of the challenges of pelvic floor training is that most men do not know where their pelvic muscles are located, what they do, how to exercise them, and what benefits exercising them may confer. In fact, many men don’t even know that they have pelvic floor muscles. Because they are out of sight, they are often out of mind and not considered when it comes to exercise and fitness. However, although concealed from view, they deserve serious respect as they are responsible for vital functions that can be enhanced when intensified by training. Pelvic floor muscle training before and after prostate cancer surgery can facilitate the resumption of urinary control and sexual function after surgery. Pelvic floor training is also useful for men who suffer with stress urinary incontinence following prostatectomy. This is a spurt-like urinary leakage that occurs at times of increased abdominal pressure, such as with sports and other high impact activities. Pelvic floor contractions on demand are a technique in which the pelvic muscles are braced and briskly engaged at the time or just before any activity that triggers the stress incontinence. When practiced diligently, this can ultimately become an automatic behavior and the incontinence improved, if not resolved.
How common is impotence? According to findings from several studies, including “The Massachusetts Male Aging Study,” overall prevalence for men between 40–70 years old is around 52 percent (or around 30 percent of all men between 18–60 years old). That’s right — nearly half of all men over 40 experience erectile dysfunction symptoms at some point. Not surprisingly, research demonstrates that impotence is increasingly prevalent with age. Around 40 percent of men in their 40s experience sexual dysfunction. Up to 70 percent of men in their 70s experience ED. (1) Every year more than 617,000 new cases of impotence occur in the United States alone.
With the advent of the “little blue pill” men’s sexual health has been thrust into the public eye and now, rather than worrying in embarrassed silence about “performance” issues, men are able to openly seek the help they need to function at their best. This is good news for the 30 million American men who suffer from erectile dysfunction or ED.1 And because 70 percent of ED cases are physiological in nature (it’s not just in your head) and often a sign of some other serious health issue, it is wise to address and correct the underlying physical imbalances that are hindering performance in the first place, ensuring both shortterm happiness and long-term health.

L-arginine is an amino acid that is necessary for the lining of the blood vessels to produce nitric oxide. Nitric oxide allows the blood vessels to relax, thus improving blood flow throughout the body, including to the penis. Studies on L-arginine and erectile dysfunction have used between 2,000-5,000 mg a day in divided doses.ii Supplemental arginine is best taken on an empty stomach.3
lung issues, neuropathy, arthritis, vision problems, thyroid dysfunction, erectile dysfunction etc. etc. are all due to depression. I think you are dead wrong! ALL of these are documented potential side effects of interferon, in the literature. Its just that the literature does not indicate that the problems might persist long term in a significant group of patients. How are you so certain that the interferon has nothing to do with these problems again????
These “sea pistachios,” as Kimmy Schmidt called them, are no joke.They’re one of the richest food sources of erection-enhancing Vitamin B12 you can find. The boner-boosting bivalves are also high in L-arginine, an amino acid that converts to nitric oxide (NO), the Marvin Gaye of naturally occurring gases: It causes blood vessels to relax and facilitate blood flow, helping you get and stay hard. Additionally, clams are high in muscle-building protein.
As men age, their estrogen levels gradually rise, while testosterone levels fall. Anti-cancer coupounds called indoles can help strike a balance. Cruciferous vegetables like broccoli are rich in indoles, which boost testosterone production by breaking down and flushing the system of excess estrogen, which inhibits the production of male sex hormones. In one study, supplementing with indole-3-carbinol from cruciferous vegetables for just 7 days cut the estrogen hormone estradiol in half for men. Another study found indole supplementation significantly increased urinary excretion of estrogens.
Yohimbe A number of clinical trials have shown that the primary component of this bark from an African tree can improve sexual dysfunction associated with selective-serotonin reuptake inhibitors (SSRIs) used to treat depression. This herb has been linked to a number of side effects, including increased blood pressure, fast or irregular heartbeat, and anxiety. Yohimbe shouldn't be used without a doctor's supervision.
×